TY - JOUR T1 - Deep cutaneous ulcers and sinus formation in an immunocompetent adult JO - Anais Brasileiros de Dermatologia T2 - AU - Zhou,Qiang AU - Zhu,Kejian SN - 03650596 M3 - 10.1016/j.abd.2018.12.003 DO - 10.1016/j.abd.2018.12.003 UR - http://www.anaisdedermatologia.org.br/en-deep-cutaneous-ulcers-sinus-formation-articulo-S0365059619300819 AB - This report describes a case of unusual deep skin ulcers with tortuous sinus tract formation in an immunocompetent woman. She was initially diagnosed with a Staphylococcus aureus skin infection and histopathologically diagnosed with pyoderma gangrenosum. However, culture from the deep end of ribbon gauze inserted into the subcutaneous sinus tract revealed shiny, light-yellow mucoid colonies, which were identified as Cryptococcus neoformans var. grubii. She was treated with fluconazole for nine months and completely healed. Cryptococcosis is an opportunistic infection caused by variants of C. neoformans species. Cutaneous manifestations of cryptococcosis are quite divergent, rarely occurring as deep skin ulcers with sinus formation. ER -