TY - JOUR T1 - Pagetoid dyskeratosis in dermatopathology JO - Anais Brasileiros de Dermatologia T2 - AU - Rocha,Tauana Ogata Coelho da AU - Moya,Fernanda Gonçalves AU - Vilella,Vívian Moreira AU - Lellis,Rute Facchini SN - 03650596 M3 - 10.1016/j.abd.2020.12.006 DO - 10.1016/j.abd.2020.12.006 UR - http://www.anaisdedermatologia.org.br/en-pagetoid-dyskeratosis-in-dermatopathology-articulo-S036505962100115X AB - Currently, pagetoid dyskeratosis is believed to involve an accelerated keratinization process, possibly induced by mechanical trauma. It represents, in almost its totality, incidental histological findings of specific cells, except when it occurs in the hands, where it usually occurs simultaneously with skin lesions and local dyschromia. These are large, rounded keratinocytes, with pale cytoplasm and a pyknotic nucleus surrounded by a clear halo, which can be easily mistaken by other skin diseases. Its etiology is not completely elucidated, and the correct identification of this entity can be of great importance in the differential diagnosis of skin disorders and the understanding of the keratinization process of the epidermis. ER -