Journal of the American Academy of Dermatology
Case ReportErosive papulonodular dermatosis associated with topical benzocaine: A report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum
Section snippets
Case 1
A 28-year-old white woman presented to our center for vulvar diseases with a 2-year history of a painful, pruritic vulvar eruption. She was initially treated by an outside physician with tacrolimus 0.1% ointment with little relief of her symptoms. The patient reported her only relief came from the use of a topical benzocaine preparation (Vagisil Anti-Itch Creme, Combe Inc, White Plains, NY) that she applied to the area several times a day. On examination of the vulva and groin area, there was
Discussion
Irritant contact dermatitis is a common cause of genital eruptions and has been estimated to represent a fifth of presenting anogenital symptoms.15, 16 Contact dermatitis of the vulva can also be a confounding factor in patients with symptoms of vulvar pruritis, irritation, or burning.16 Vulvar skin is more readily irritated than skin on the trunk and extremities, presumably a result of decreased barrier function as compared with other anatomic sites.17, 18, 19 We believe the erosive
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Case Report: An Uncommon Etiology of Vulvar Irritation and Swelling in an Adolescent Patient
2022, Journal of Pediatric and Adolescent GynecologyCitation Excerpt :Adverse outcomes after chronic topical benzocaine use have been described in the adult population. Robson et al described 2 patients who presented with significant skin changes.6 They reported the case of a 28-year-old woman with painful, pruritic vulvar irritation prompting her to apply topical benzocaine several times per day.
Perivulvar Pseudoverrucous Papules and Nodules in a 4-Year-Old Girl with Urinary and Fecal Incontinence: Case Report
2022, Journal of Pediatric and Adolescent GynecologyCitation Excerpt :Similar to chronic (diaper) dermatitis, PPNs tend to occur where skin barriers and dermal thickness are decreased (such as in the genital area) compared with other parts of the body.9,12 Case reports from the literature suggest that the gross appearance of PPNs can be quite variable and mistaken for other irritant dermatoses associated with fecal and urinary incontinence (Jacquet's erosive dermatitis and granuloma gluteale infantum) or as manifestations of STIs.2,9 It is paramount to rule out HPV infection and secondary syphilis (condylomata lata) given the implications of sexual abuse in a pediatric patient.
Infiltrated plaques on the lateral aspects of the hips disclosing a case of adult gluteal granuloma
2021, Anais Brasileiros de DermatologiaNoninfectious Peritoneal Dialysis Exit Site Rash—An Unusual Case Report and Review of the Literature
2018, Kidney International ReportsCitation Excerpt :Granuloma gluteale aldutorum is part of the erosive papulonodular dermatosis disease spectrum and is believed to be from irritant contact dermatitis. It has been described in children as diaper rash8 and in adults with irritation of the skin from urine or topical benzocaine use.9 Granuloma gluteale infantum/adultorum is an uncommon proliferative reactive condition in response to severe chronic irritant contact dermatitis, which is usually seen in the anogenital region of patients with chronic diarrhea and or urinary incontinence.
Napkin dermatitis
2015, Annales de Dermatologie et de Venereologie
Production and distribution supported by an educational grant to the American Academy of Dermatology by Stiefel Laboratories, Inc.
Funding sources: None.
Conflicts of interest: None identified.