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Alopecia areata (AA) and treatment with simvastatin/ezetimibe: Experience of 20 patients

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Cited by (30)

  • Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology

    2020, Anais Brasileiros de Dermatologia
    Citation Excerpt :

    Follow-up with G6PD, blood count, biochemistry, and hepatogram assessment are essential to monitor possible adverse effects. Data on the efficacy of the combination of simvastatin 40 mg/ezetimibe 10 mg, 1 ×/day in the treatment of AA are limited and controversial.74–77 Positive reports show hair regrowth rates and lower relapse in patients with recent onset and good prognosis for AA.74,75

  • Novel therapies for alopecia areata: The era of rational drug development

    2018, Journal of Allergy and Clinical Immunology
    Citation Excerpt :

    This is believed to contribute to its superiority in suppressing atherosclerosis, which can have a significant TH17 component. Initial reports on the efficacy of this treatment in patients with AA were negative32; however, the results of a more robust and controlled clinical trial are awaited (Clinical Trial no. NCT01520077). When patients receiving topical bimatoprost for open-angle glaucoma and ocular hypertension unexpectedly reported longer and thicker lashes as a side effect,33 the hair research community quickly focused their efforts on uncovering a role for prostaglandin F2α in accelerating anagen hair growth and stimulating follicular melanocyte stem cells.34

  • Treatment of Alopecia Areata with Simvastatin/Ezetimibe

    2018, Journal of Investigative Dermatology Symposium Proceedings
    Citation Excerpt :

    Inhibition of natural killer cell cytotoxicity is another likely mechanism (Lattouf et al., 2015; Namazi, 2004) We retrieved six articles detailing the use of statins for the treatment of AA, including two case reports (Ali and Martin, 2010; Robins, 2007), three small case series (Freitas Gouveia and Trüeb, 2017; Lattouf et al., 2015; Loi et al., 2016), and an anecdotal account (Camacho, 2017) (Table 2). The first documented case (2007) involved a 54-year-old man with AA universalis and uncontrolled hyperlipidemia who achieved significant hair regrowth 1 month after combination simvastatin/ezetimibe was initiated (Robins, 2007).

  • Big Data Reveal Insights into Alopecia Areata Comorbidities

    2018, Journal of Investigative Dermatology Symposium Proceedings
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Conflicts of interest: None declared.

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