A 53-year-old man presented with a recurrent papulovesicular pruritic rash located on his trunk, which was exacerbated by heat and sweating. These clinical features were suggestive of Grover disease (GD) (Fig 1).
Two different dermoscopic patterns were found (Figs 2, B; 3, B; and 4, B). Early lesions were mainly typified by a pinkish-white background with polymorphous vessels, which could be linear, glomerular, or hairpin (Fig 2, B); whereas late stage lesions had a pinkish-yellow background, a yellowish central keratotic plug (described as a plug with a central, yellowish to brown, star-like pattern),1, 2 and a white radiating pattern with linear and hairpin vessels (Figs 3, B and 4, B).
Histopathologic examination of the early lesion (Fig 2, C) and two of the late-stage lesions was performed (Figs 3, C; 4, C; and 4, D). The spectrum of dermoscopic and histopathologic characteristics of early and late stage GD lesions suggest that the lesions evolve from an unspecific initial appearance to a specific late stage appearance. These clinical, dermoscopic, and histopathologic specific findings reveal two progressive patterns. In early stages, central glomerular, linear,Key message
Publication of this article was supported by 3Gen Inc.
Funding sources: None.
Conflicts of interest: None declared.
