Colon atresia and frontal encephalocele: a rare association
Section snippets
Case report
A 2.7-kg term male neonate was born at 38 weeks gestation. The pregnancy had been normal, and there was no history of varicella exposure or other infections. Abdominal distension, bile vomiting, the absence of meconium in a rectal washout and dilated bowel loops prompted a contrast enema, which showed a microcolon with cessation of filling in the left upper quadrant (Fig. 1).
At laparotomy, a type III cecal atresia was found. The remainder of the ascending colon and the transverse colon were
Discussion
The theory of an embryologic vascular insult resulting in intestinal atresia is certainly attractive and has been reproduced in animal models [13], [14]. However, it fails to provide an etiological mechanism for the frequent association of CA with other congenital anomalies, both intestinal and extraintestinal anomalies [2]. It is possible, therefore, that the pathogenesis of CA could have more than 1 mechanism, accounting for the variety of phenotypes [15], [16]. The studies of Puri and
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Cited by (2)
Colonic stenosis in infant with connective tissue disorder
2013, Journal of Pediatric Surgery Case ReportsCitation Excerpt :Colonic atresia has been associated with abnormalities of the musculoskeletal system (syndactyly, polydactyly, clubfoot, absent radius, absent hand, heart), as well as craniofacial anomalies (facial hemiaplasia, anophthalmia) [9–12]. This has led to the speculation that although a vascular insult may explain many cases of colonic atresia, another mechanism such as an early embryonal disruption may lead to the phenotype with a variety of anomalies [11–13]. The present case may also support this theory of a common genetic origin as responsible for this constellation of anomalies.
Differences in the Outcome of Colonic Atresia with and without Abdominal Wall Defects
2022, European Journal of Pediatric Surgery