Clinical and laboratory observation
Hyperzincemia in a patient with pyoderma gangrenosum

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Cited by (13)

  • Hyperzincaemia and hypercalprotectinaemia: A new disorder of zinc metabolism

    2002, Lancet
    Citation Excerpt :

    This study had no specific funding source. Table 1 shows the clinical and laboratory data of patients, with the patient described by Hambidge and colleagues4 included for comparison. All patients presented with recurrent infections, hepatosplenomegaly, arthritis, anaemia, and persistently raised concentrations of C-reactive protein.

  • Hyperzincemia with systemic inflammation: A heritable disorder of calprotectin metabolism with rheumatic manifestations?

    2002, Journal of Pediatrics
    Citation Excerpt :

    Familial hyperzincemia without clinical symptoms has been reported in a few instances in which excessive zinc was found in the albumin-rich fractions.1,2 On the other hand, there are two sporadic case reports of hyperzincemia with multiorgan inflammation showing increased zinc binding in the α2-macroglobulin-rich fractions3,4 (Table). Hypercalprotectinemia was recently confirmed to be causative for the hyperzincemia,6 and it is also present in the present patient and his mother.

  • Zinc

    1986, Trace Elements in Human and Animal Nutrition: Fifth Ed.
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Supported by Grant 5 R22 AM12432 from the National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases and by Grant RR-69 from the General Clinical Research Center, National Institute of Health.

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