Clinical and laboratory observationHyperzincemia in a patient with pyoderma gangrenosum†
References (3)
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Zinc in psoriasis
Lancet
(1970)
Cited by (13)
Hyperzincaemia and hypercalprotectinaemia: A new disorder of zinc metabolism
2002, LancetCitation Excerpt :This study had no specific funding source. Table 1 shows the clinical and laboratory data of patients, with the patient described by Hambidge and colleagues4 included for comparison. All patients presented with recurrent infections, hepatosplenomegaly, arthritis, anaemia, and persistently raised concentrations of C-reactive protein.
Hyperzincemia with systemic inflammation: A heritable disorder of calprotectin metabolism with rheumatic manifestations?
2002, Journal of PediatricsCitation Excerpt :Familial hyperzincemia without clinical symptoms has been reported in a few instances in which excessive zinc was found in the albumin-rich fractions.1,2 On the other hand, there are two sporadic case reports of hyperzincemia with multiorgan inflammation showing increased zinc binding in the α2-macroglobulin-rich fractions3,4 (Table). Hypercalprotectinemia was recently confirmed to be causative for the hyperzincemia,6 and it is also present in the present patient and his mother.
A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome
1997, Mayo Clinic ProceedingsPyoderma gangrenosum occurring at multiple surgical incision sites
1987, GastroenterologyZinc
1986, Trace Elements in Human and Animal Nutrition: Fifth Ed.Extensive pyoderma gangrenosum-like lesions revealing a case of hyperzincemia and hypercalprotectinemia: when to suspect it?
2019, Anais Brasileiros de Dermatologia
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Supported by Grant 5 R22 AM12432 from the National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases and by Grant RR-69 from the General Clinical Research Center, National Institute of Health.