Journal of the American Academy of Dermatology
Spores and mycelia in cutaneous chromomycosis☆,☆☆,★
Section snippets
Case 1
A 62-year-old man first noted an occasionally pruritic “wartlike” papule on his left forearm 10 years previously. The lesion gradually increased in size until it covered the majority of his forearm (Fig 1). Social history revealed that the patient was employed outdoors and was an avid gardener. Past medical history, including risk factors for immunosuppression, was entirely negative. Several scrapings taken from the verrucous, scaly border of the skin lesion revealed
DISCUSSION
Chromomycosis (or chromoblastomycosis) is a slowly progressive cutaneous mycosis caused by various dematiaceous (pigmented) fungi. The primary lesion is thought to develop as a result of percutaneous traumatic inoculation.6 Rarely, chromomycosis may involve the central nervous system, generally without concomitant skin involvement.7, 8 This cerebral variant is usually due to Cladosporium trichoides . Unlike phaeohyphomycosis (infection by other dematiaceous fungi), chromomycosis reportedly does
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Cited by (24)
Subcutaneous phaeohyphomycosis caused by Alternaria section Alternaria
2023, International Journal of Infectious DiseasesPresence of hyphae in chromoblastomycosis examinations: an enigma to be solved
2021, Anais Brasileiros de DermatologiaChromoblastomycosis: An etiological, epidemiological, clinical, diagnostic, and treatment update
2018, Anais Brasileiros de DermatologiaCitation Excerpt :Fungal cells with their characteristic micromorphology – round, dark-brown, thick-walled, 4-12 microns in diameter and with multiplanar reproduction, called muriform (sclerotic) bodies – are found in intraepidermal microabscesses in multinucleated Langhans and/or foreign body-type cells, in suppurative or tuberculoid granulomas, easily identified by hematoxylin-eosin staining (Figure 11C). Dimorphism may be observed, and it is possible to identify hyphae and muriform bodies in material from skin lesions.94 Pires et al., in a study of 65 patients that underwent histopathological examination with HE staining, found two main types of granulomatous tissue reaction: suppurative granuloma with abundant fungal cells, mostly from verrucous lesions, and tuberculoid granuloma, with few parasites, from plaque and atrophic lesions.95
Mycoses and algal infections
2009, Weedon's Skin Pathology: Third EditionVinyl adhesive tape also effective for direct microscopy diagnosis of chromomycosis, lobomycosis, and paracoccidioidomycosis
2005, Diagnostic Microbiology and Infectious Disease
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This article is made possible through an educational grant from Ortho Dermatological.
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Reprint requests: Sylvia Hsu, MD, Department of Dermatology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030
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